Ryan Reynolds/YouTube; ABC Photo Archives/Disney General Entertainment Content via Getty Ryan Reynolds in 'Doogie Howser M.D.' spoof; Neil Patrick Harris in a 1989 photo from the real thing More ...

And since Neil Patrick Harris is filling that role in the newly announced Marvel’s Deadpool VR, Reynolds responded exactly how you’d imagine: by taking over as Doogie Howser.

Step aside, Ryan Reynolds, because famed sitcom star Neil Patrick Harris will officially portray Marvel's infamous Merc with a Mouth in an upcoming VR game.

Neil Patrick Harris: I read the script with one hand covering my eye and shook my head at the depiction of who these writers thought I was.

A VR game based on Marvel's "Deadpool" franchise is set to launch later this year from Meta Quest with Neil Patrick Harris starring.

Ryan Reynolds spoofs “Doogie Howser M.D.”, calls Neil Patrick Harris a 'butthole' for stealing Deadpool game role Harris is set to voice the merc with a mouth in 'Marvel’s Deadpool VR' for ...

Developed by Twisted Pixel and Oculus Studios, in collaboration with Marvel Games, “Marvel’s Deadpool VR” features a new story focused around the MCU character portrayed by Ryan Reynolds in ...