Children were recently discovered to have been exposed to high levels of lead in Milwaukee schools — the latest episode in an ongoing toxic pandemic. This time, no help was forthcoming from the CDC.

Real-world data could help advance disease prevention and treatment, enhance quality of care, and empower patients to improve their health. But various challenges continue to impede their utilization.

Fragile X disorders include two distinct conditions: fragile X syndrome (the most common single-gene cause of developmental ...

The author describes pronuclear transfer, a type of mitochondrial donation, which was made available to women with mitochondrial DNA disease in a reproductive care pathway implemented in Newcastle, ...

Children born to women who carry pathogenic variants in mitochondrial DNA (mtDNA) are at risk for a range of clinical syndromes collectively known as mtDNA disease. Mitochondrial donation by pronuc ...

We report a method for the recovery of hearts for transplantation from deceased donors after circulatory death that obviates the need for thoracoabdominal normothermic regional perfusion or ex situ ...

Pathogenic variants in mitochondrial DNA (mtDNA) are a common cause of severe, often fatal, inherited metabolic disease. A reproductive care pathway was implemented to provide women carrying pathog ...

In 15 patients with primary aldosteronism, baxdrostat (a second-generation, nonimidazole aldosterone synthase inhibitor) resolved or reduced the severity of hypertension, excessive aldosterone ...

AI mammography aids are being sold as additions to mammography screening, with direct-to-consumer marketing touting improved cancer-detection rates, despite a lack of evidence of clinical effective ...

Endovascular thrombectomy has been shown to be safe and effective in selected patients with acute ischemic stroke due to large-vessel occlusion (LVO) up to 24 hours after symptom onset.1 In pivotal ...

During 2018–2024, the percentage of N. gonorrhoeae isolates carrying tetM, which confers tetracycline resistance, increased from less than 10% to more than 30% across the United States.

Cardiovascular diseases, principally ischemic heart disease and stroke, have consistently been the leading cause of death worldwide since 1990 and accounted for 19.8 million deaths in 2022 alone.1 ...