New England Revolution (6-8-7, 10th in the Eastern Conference) vs. New York Red Bulls (8-8-6, seventh in the Eastern Conference) ...

New York City FC (9-8-4, sixth in the Eastern Conference) vs. Orlando City SC (9-5-8, fifth in the Eastern Conference) ...

Vancouver Whitecaps FC (11-5-5, fourth in the Western Conference) vs. Houston Dynamo (7-10-5, 11th in the Western Conference) ...

Real Salt Lake (7-10-4, 12th in the Western Conference) vs. Portland Timbers (9-6-6, fifth in the Western Conference) ...

Inter Miami CF (11-3-5, fourth in the Eastern Conference) vs. FC Cincinnati (13-6-3, second in the Eastern Conference) ...